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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
2-8℃
- 保质期:
见包装
- 英文名:
Evodiamine吴茱萸碱
- 库存:
大量现货
- 供应商:
上海研谨生物
- CAS号:
518-17-2
- 规格:
20mg
吴茱萸碱
分析标准品,HPLC≥98%
Evodiamine
CAS号:518-17-2
分子式:C19H17N3O
分子量:303.36
MDL:MFCD06407824
别名:吴茱萸胺
|
货号 |
规格/参数/品牌 |
价格 |
货期 |
|
YJ-B21315-20mg |
分析标准品,HPLC≥98% |
¥360.00 |
现货 |
|
YJ-B21315-100mg |
分析标准品,HPLC≥98% |
¥1040.00 |
现货 |
|
JS31472-1g |
≥98% |
¥260.00 |
现货 |
|
JS31472-5g |
≥98% |
¥510.60 |
现货 |
|
JS31472-25g |
≥98% |
¥1500.60 |
现货 |
|
JA10150-20mg |
分析标准品,含量98.7%,可溯源 |
¥5600.00 |
现货 |
产品介绍
药理药效:吴茱萸碱有健胃、镇痛、止干呕和止嗳酸等功效;有利尿作用;对大肠杆菌有强力的 抑制作用;对猪蛔虫有显著杀虫作用;还有收缩子宫及升压作用 。治疗早老性痴呆症及中风有一定疗效。
熔点: 263-265°C
沸点: 575.1°C at 760 mmHg
比旋光度: D15 +352° (acet##one); D +440° (chloroform)
外观: 白色针晶(氯仿)
溶解性: 溶于丙ton,微溶于乙醇、乙mi、氯仿,几乎不溶于水、石油mi、苯
敏感性: 对光敏感
储存条件: 2-8℃
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文献和实验参考文献(22篇)
22. [IF=6.7] Guoliang Cui et al."Berberine In Combination With Evodiamine Ameliorates Gastroesophageal Reflux Disease Through TAS2R38/TRPV1-Mediated Regulation of MAPK/NF-κB Signaling Pathways and Macrophage Polarization."PHYTOMEDICINE.2024 Nov;:156251
21. [IF=4.8] Yan Wang et al."Activating TRPV1 by evodiamine attenuates atherosclerosis by inhibiting endothelial microparticle release."INTERNATIONAL IMMUNOPHARMACOLOGY.2025 May;155:114657
20. [IF=4.9] Xiaoran Zhao et al."Constructing a hydrogel based on self-assembly properties of glycyrrhizic acid: A drug delivery system with digestive tract responsive."COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS.2024 Sep;697:134497
19. [IF=6.8] Qiqi Fan et al."Metabolic characteristics of evodiamine were associated with its hepatotoxicity via PPAR/PI3K/AKT/NF-кB/tight junction pathway-mediated apoptosis in zebrafish."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY".2024 Jul;279:116448
18. [IF=4.3] Peng Ting et al."Elucidation of the relationship between evodiamine-induced liver injury and CYP3A4-mediated metabolic activation by UPLC-MS/MS analysis."ANALYTICAL AND BIOANALYTICAL CHEMISTRY.2023 Jul;:1-17
17. [IF=11.072] Qiang Yu et al."A deep eutectic solvent binary-phase system for alkaloid extraction from Chinese herb Evodia lepta residue and its mechanism."Journal of Cleaner Production.2023 Apr;398:136645
16. [IF=2.838] Wang Shuo et al."Toxicity and toxicokinetics of the ethanol extract of Zuojin formula."BMC Complementary Medicine and Therapies.2022 Dec;22(1):1-14
15. [IF=3.024] Xuan Yu et al."An innovative extraction strategy for herbal medicine by adopting p-sulphonatocalix[6]/[8]arenes."PHYTOCHEMICAL ANALYSIS
14. [IF=4.05] Xingming Hou et al."Evodiamine Lowers Blood Lipids by Up-Regulating the PPARγ/ABCG1 Pathway in High-Fat-Diet-Fed Mice."J Nat Prod. 2021;XXXX(XXX):XXX-XXX
13. [IF=2.952] Yongfeng Zhang et al."Protection against ulcerative colitis and colorectal cancer by evodiamine via anti‑inflammatory effects."Mol Med Rep. 2022 May;25(5):1-14
12. [IF=4.432] Zhijun Zhao et al."Identification of evodiamine and rutecarpine as novel TMEM16A inhibitors and their inhibitory effects on peristalsis in isolated Guinea-pig ileum."Eur J Pharmacol. 2021 Oct;908:174340
11. [IF=4.183] Yongfeng Zhang et al."Pharmacological Basis for the Use of Evodiamine in Alzheimer’s Disease: Antioxidation and Antiapoptosis."Int J Mol Sci. 2018 May;19(5):1527
10. Zhang Y, Wang J, Wang C, Li Z, Liu X, Zhang J, Lu J, Wang D. Pharmacological Basis for the Use of Evodiamine in Alzheimer’s Disease: Antioxidation and Antiapoptosis. International Journal of Molecular Sciences. 2018; 19(5):1527. ##**doi.org/10.3390/ijm
9. 陈永顺,杨金霞,吴珍.吴茱萸碱水凝胶贴剂的研制及质量评价[J].中国药师,2021,24(03):571-574.
8. 周建新,沈硕,杜茂波,李玉洁,孙奕,何爱萍,姚瑶,王明硕,刘淑芝,尹永芹.基于UPLC-Q-TOF-MS技术和整合药理学方法探索吴茱萸经皮成分及其治疗腹泻的分子机制[J].中国实验方剂学杂志,2021,27(07):112-120.
7. 徐国波,雷丹丹,肖耀华,陈广桂,何迅,廖尚高.良姜胃疡胶囊高效液相色谱特征指纹图谱研究[J].中南药学,2020,18(09):1503-1507.
6. 刘璐,王雪梅,王岩,席红梅,郭建多,黄求进.吴茱萸碱对胶质瘤SHG-44细胞凋亡的促进作用及其机制[J].中国医学科学院学报,2020,42(05):591-595.
5. 张红梅, 李国, 宋龙, et al. 贵州和浙江产吴茱萸指纹图谱分析及含量测定[J]. 中国实验方剂学杂志, 2014, 20(017):69-73.
4. 张红梅 李国 宋龙 等. 吴茱萸与伪品臭辣树果实的生药学鉴定[J]. 中药材 2016(3期):515-518.
3. 曹志 杨伊林 王穗暖 等. 吴茱萸碱对人胶质瘤U251细胞增殖及凋亡影响的研究[J]. 临床神经外科杂志 2014.
2. 顾家毓 余丹丹 邬瑞光. 吴茱萸碱与脂质体模拟生物膜的相互作用:FTIR和DSC研究[J]. 光谱学与光谱分析 2019 39(006):1757-1762.
1. 张婧怡 林淑娴 侯化化 等. 吴茱萸总碱抑制大鼠左室肥厚及对钙调神经磷酸酶信号通路的影响[J]. 遵义医学院学报 2014 37(002):151-155.
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