pH荧光探针Protonex 红 780 酸

pH荧光探针Protonex 红 780 酸

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  • ¥2022
  • AAT Bioquest
  • 进口
  • 21185
  • 2025年07月15日
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    • 详细信息
    • 技术资料
    • 英文名

      Protonex™ Red 780 acid

    • 库存

      50

    • 供应商

      广州市左克生物科技发展有限公司

    • 规格

      1mg

    产品参数
    Ex (nm)-Em (nm)-
    分子量N/A溶剂DMSO
    存储条件在零下15度以下保存, 避免光照
    产品概述

    产品基本信息

    产品名称:Protonex 红 780 酸

    储存条件:-15℃避光防潮

    保质期:12个月

     

    产品物理化学光谱特性

    分子量:655.84

    外观:固体

    溶剂:DMSO

    激发波长(nm):N/A

    发射波长(nm):N/A

     

    产品介绍

    Protonex Red 780 的工作原理是根据环境 pH 值改变其荧光强度。 Protonex Red 780 在碱性 pH 值下荧光最小,在酸性 pH 下荧光最大。当 Protonex Red 780 与细胞表面的受体或抗体结合时,它基本上不发出荧光,因为细胞外 pH 值为中性。然而,当受体或抗体响应刺激而内化到细胞中时,它会进入内体途径,其中 pH 值为酸性。这使得 Protonex Red 780 在被红色激光激发时变得高度荧光并发射近红外光。通过测量 Protonex Red 780 的荧光强度,可以监测活细胞中受体或抗体的激活和运输。 Protonex Red 780 在研究 G 蛋白偶联受体 (GPCR)(最流行的治疗药物靶点之一)的激活和运输方面特别有用。 Protonex Red 780 可用于标记任何受体或表位标签抗体,并监测其在激动剂刺激下从细胞表面进入酸性内体的运动。 Protonex Red 780 还可用于测量活细胞中不同 GPCR 的高效激动剂和拮抗剂反应。,为您提供优质的Protonex 红 780 酸。 

     

    溶解方案(溶剂以说明书为准)

      0.1 mg 0.5 mg 1 mg 5 mg 10 mg
    1 mM 152.476 µL 762.381 µL 1.525 mL 7.624 mL 15.248 mL
    5 mM 30.495 µL 152.476 µL 304.952 µL 1.525 mL 3.05 mL
    10 mM 15.248 µL 76.238 µL 152.476 µL 762.381 µL 1.525 mL

     

    参考文献

    Mechanisms of 15-Epi-LXA4-Mediated HO-1 in Cytoprotection Following Inflammatory Injury.
    Authors: Wang, Meng and Tong, Kun and Chen, Zhe and Wen, Zhengde
    Journal: The Journal of surgical research (2023): 245-255
     
    Generalization of the Ratiometric Method to Extend pH Range Measurements of the BCECF Probe.
    Authors: Tafech, Alaa and Beaujean, Céline and Usson, Yves and Stéphanou, Angélique
    Journal: Biomolecules (2023)
     
    The phosphoinositide PI(3,5)P2 inhibits the activity of plant NHX proton/potassium antiporters: Advantages of a novel electrophysiological approach.
    Authors: Gradogna, Antonella and Pardo, José M and Carpaneto, Armando
    Journal: Biomolecular concepts (2022): 119-125
     
    Biochemical properties of H+-Ca2+-exchanger in the myometrium mitochondria.
    Authors: Danylovych, Yurii V and Danylovych, Hanna V and Kolomiets, Oksana V and Sviatnenko, Marina D and Kosterin, Sergiy O
    Journal: Current research in physiology (2022): 369-380
     
    FLIM for Evaluation of Difference in Metabolic Status between Native and Differentiated from iPSCs Dermal Papilla Cells.
    Authors: Kashirina, Alena and Gavrina, Alena and Mozherov, Artem and Kozlov, Dmitriy and Kuznetsova, Daria and Vorotelyak, Ekaterina and Zagaynova, Elena and Kalabusheva, Ekaterina and Kashina, Aleksandra
    Journal: Cells (2022)
     
    mOrange2, a Genetically Encoded, pH Sensitive Fluorescent Protein, is an Alternative to BCECF-AM to Measure Intracellular pH to Determine NHE3 and DRA Activity.
    Authors: Sarker, Rafiquel and Tse, Chung Ming and Lin, Ruxian and McNamara, George and Singh, Varsha and Donowitz, Mark
    Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (2022): 39-49
     
    RNA-seq analysis reveals genes related to photosynthetic carbon partitioning and lipid production in Phaeodactylum tricornutum under alkaline conditions.
    Authors: Liu, Jian and Yin, Weihua and Zhang, Xinya and Xie, Xuan and Dong, Guanghui and Lu, Yao and Tao, Baoxiang and Gong, Qiangbin and Chen, Xinyan and Shi, Chao and Qin, Yuan and Zeng, Rensen and Li, Dawei and Li, Hongye and Zhao, Chao and Zhang, Huiying
    Journal: Frontiers in microbiology (2022): 969639
     
    ClC-K2 Cl- channel allows identification of A- and B-type of intercalated cells in split-opened collecting ducts.
    Authors: Pyrshev, Kyrylo and Khayyat, Naghmeh Hassanzadeh and Stavniichuk, Anna and Tomilin, Viktor N and Zaika, Oleg and Ramkumar, Nirupama and Pochynyuk, Oleh
    Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology (2022): e22275
     
    Characterization of intracellular buffering power in human induced pluripotent stem cells and the loss of pluripotency is delayed by acidic stimulation and increase of NHE1 activity.
    Authors: Lee, Shiao-Pieng and Chao, Shih-Chi and Chou, Mei-Fang and Huang, Shu-Fu and Dai, Niann-Tzyy and Wu, Gwo-Jang and Tsai, Chien-Sung and Loh, Shih-Hurng and Tsai, Yi-Ting
    Journal: Journal of cellular physiology (2021): 1515-1528
     
    Energy Metabolism and Intracellular pH Alteration in Neural Spheroids Carrying Down Syndrome.
    Authors: Kashirina, Alena and Gavrina, Alena and Kryukov, Emil and Elagin, Vadim and Kolesova, Yuliya and Artyuhov, Alexander and Momotyuk, Ekaterina and Abdyyev, Vepa and Meshcheryakova, Natalia and Zagaynova, Elena and Dashinimaev, Erdem and Kashina, Aleksandra
    Journal: Biomedicines (2021)

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