Cy5醛

产品基本信息

产品名称：Cy5醛

储存条件：-15℃避光防潮

保质期：24个月

 

产品物理化学光谱特性

分子量：839.94

溶剂：DMSO

激发波长(nm)：651

发射波长(nm)：670

消光系数（cm-1 M-1）:250000

荧光量子产率：0.27（PBS）,0.4(乙醇)

校正因子 (280 nm)：0.03

 

产品介绍

Cy5醛是一种可与胺，肼或羟胺反应的活性红色荧光染料。醛基可与pH 5-9的胺，酰肼或羟胺基反应。与胺反应性琥珀酰亚胺基酯基（NHS）不同，醛可以在酸性pH下与N端胺基反应，这是某些生物缀合反应有时需要的条件。醛与胺基反应形成席夫碱。用氢化物进一步还原将形成稳定的C-N键。醛与其他基团之间的反应可实现荧光素染料的位点特异性缀合和标记，使其靶向分子上的所需位置。缀合Cy5染料可以通过Cy5通道下的普通荧光仪器轻松检测到。

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参考文献

[Microanalysis of Acetaldehyde Dehydrogenase 2 Genotype Based on SNaPShot-FCA].
Authors: Zeng, Shu-Shu and Gao, Xiu-Feng and Zhang, You and Feng, Chuan-Rui and Luo, Ya-Xiong and Wu, Xiao-Ting and Li, Yong-Sheng
Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition (2019): 737-742

pH responsible and fluorescent Cy5.5-PEG-g-A-HA/CDDP complex nanoparticles: synthesis, characterization, and application for targeted drug delivery.
Authors: Cheng, Cui and Meng, Yabin and Zhang, Zhihong and Li, Ya and Liu, Chun and Zhang, Qiqing
Journal: Journal of materials science. Materials in medicine (2019): 58

Tumoral Acidic pH-Responsive cis-Diaminodichloroplatinum-Incorporated Cy5.5-PEG- g-A-HA Nanoparticles for Targeting Delivery of CDDP against Cervical Cancer.
Authors: Cheng, Cui and Meng, Yabin and Zhang, Zhihong and Li, Ya and Zhang, Qiqing
Journal: ACS applied materials & interfaces (2018): 26882-26892

Sensitive Detection of Polynucleotide Kinase Activity by Paper-Based Fluorescence Assay with λ Exonuclease Assistance.
Authors: Zhang, Hua and Zhao, Zhen and Lei, Zhen and Wang, Zhenxin
Journal: Analytical chemistry (2016): 11358-11363

Sensitive detection of histamine using fluorescently labeled oxido-reductases.
Authors: Gustiananda, Marsia and Andreoni, Alessio and Tabares, Leandro C and Tepper, Armand W J W and Fortunato, Luca and Aartsma, Thijs J and Canters, Gerard W
Journal: Biosensors & bioelectronics (2012): 419-25

An efficient strategy for sequencing-by-synthesis.
Authors: Gao, Li and Lu, Hua and Xu, Lijian and Lu, Zuhong
Journal: Journal of nanoscience and nanotechnology (2010): 2988-93

Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation.
Authors: Chouchani, Edward T and Hurd, Thomas R and Nadtochiy, Sergiy M and Brookes, Paul S and Fearnley, Ian M and Lilley, Kathryn S and Smith, Robin A J and Murphy, Michael P
Journal: The Biochemical journal (2010): 49-59

Protein thiol oxidation in murine airway epithelial cells in response to naphthalene or diethyl maleate.
Authors: Spiess, Page C and Morin, Dexter and Williams, Chase R and Buckpitt, Alan R
Journal: American journal of respiratory cell and molecular biology (2010): 316-25

Chemical derivatization of compact disc polycarbonate surfaces for SNPs detection.
Authors: Bañuls, María-José and García-Piñón, Francisco and Puchades, Rosa and Maquieira, Angel
Journal: Bioconjugate chemistry (2008): 665-72

Identification and characterization of Clostridium perfringens using single target DNA microarray chip.
Authors: Al-Khaldi, Sufian F and Villanueva, Doralis and Chizhikov, Vladimir
Journal: International journal of food microbiology (2004): 289-96