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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Y box binding protein 1
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
O95498
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP,IF
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
Y box binding protein 1
- 抗体英文名:
anti-YBX1 antibody,YBX1 antibody
- 抗体名:
anti-YBX1 抗体,YBX1 抗体
- 规格:
100μl
YBX1抗体| YBX1 antibody
货号 PAab09561
蛋白别名 BP 8 antibody, CBF A antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, DNA binding protein B antibody, EFI A antibody, Enhancer factor I subunit A antibody, MDR NF1 antibody, NSEP 1 antibody, NSEP1 antibody, Y box binding protein 1 antibody, Y box transcription factor antibody, YB 1 antibody, YB1 antibody, YBX1
蛋白介绍
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.
产品描述
anti-YBX1 antibody is a Rabbit Polyclonal antibody againstYBX1..
建议稀释比例
WB:1:500-1:5000;IP:1:200-1:2000;IHC:1:20-1:200;IF:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human placenta using PAab09561(YBX1 antibody) at dilution of 1:100
Western blot
MCF7 cells were subjected to SDS PAGE followed by western blot with PAab09561(YBX1 antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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