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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
matrix metallopeptidase 13 (collagenase 3)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat,Zebrafish
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P15248
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,IHC,WB,IF
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
matrix metallopeptidase 13 (collagenase 3)
- 抗体英文名:
anti-MMP13 antibody,MMP13 antibody
- 抗体名:
anti-MMP13 抗体,MMP13 抗体
- 规格:
100μg
MMP13抗体| MMP13 antibody
货号 PAab05235
蛋白别名
蛋白介绍
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CTGF. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
产品描述
anti-MMP13 antibody is a Rabbit Polyclonal antibody againstMMP13..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human breast cancer using PAab05235(MMP13 antibody) at dilution of 1:50
Western blot
MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with PAab05235( MMP13 Antibody) at dilution of 1:600(本抗体仅供体外科研用途,不可用于临床诊断!) <"">
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