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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
WD repeat domain 5
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
O95498
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
WD repeat domain 5
- 抗体英文名:
anti-WDR5 antibody,WDR5 antibody
- 抗体名:
anti-WDR5 抗体,WDR5 抗体
- 规格:
100μl
WDR5抗体| WDR5 antibody
货号 PAab09497
蛋白别名 WDR5 antibody, BIG3 antibody, BMP2 induced 3 kb gene protein antibody, WD repeat containing protein 5 antibody, SWD3
蛋白介绍
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation.
产品描述
anti-WDR5 antibody is a Rabbit Polyclonal antibody againstWDR5..
建议稀释比例
WB : 1:500-1:5000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human brain using PAab09497(WDR5 antibody) at dilution of 1:100
Western blot
NIH/3T3 cells were subjected to SDS PAGE followed by western blot with PAab09497(WDR5 antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验NCB | 上交陈国强院士课题组揭示著名抑癌基因 PTEN 异构体 PTENα/β,有促进肿瘤生长的作用
和 146 个氨基酸序列,翻译成两个更长的异构体,PTENα 和 PTENβ3。此前,这两种异构体的在癌症的功能及机制依然不明。PTEN 异构体结构 4图片来源:Nature Cell Biology2019 年 11 月 4 日,上海交通大学副校长陈国强院士课题组在 Nature Cell Biology 发表了题为《PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation》的长文 5。该文首次报道
Array‐Based High‐Throughput Screening in Mouse Embryonic Stem Cells with shRNAs
0.1% (v/v) Triton X‐100 in PBS Primary antibody Bovine serum albumin or serum corresponding to the species
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