- ￥2260
- LSM Bio
- 进口
- PAab09187
- 2025年07月16日
- ELISA,WB
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
ubiquitin-conjugating enzyme E2 variant 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
ubiquitin-conjugating enzyme E2 variant 1
- 抗体英文名：
anti-UBE2V1 antibody,UBE2V1 antibody
- 抗体名：
anti-UBE2V1 抗体,UBE2V1 抗体
- 规格：
100μl
UBE2V1抗体| UBE2V1 antibody
货号 PAab09187
蛋白别名 CIR1 antibody, CROC 1 antibody, CROC1 antibody, UBE2V antibody, UBE2V1 antibody, UEV 1 antibody, UEV1 antibody, UEV1A
蛋白介绍
Has no ubiquitin ligase activity on its own. The UBE2V1- UBE2N heterodimer catalyzes the synthesis of non-canonical poly- ubiquitin chains that are linked through Lys-63. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes.
产品描述
anti-UBE2V1 antibody is a Rabbit Polyclonal antibody againstUBE2V1..
建议稀释比例
WB : 1:500-1:5000;IHC:1:50-1:200；IF：1:10-1:100
IHC
Immunohistochemistry of paraffin-embedded human lung cancer slide using PAab09187( CD44 Antibody) at dilution of 1:50
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab09187(CD44 antibody) at dilution of 1:1000(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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