UBE2S| UBE2S antibody
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UBE2S| UBE2S antibody

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  • ¥2260
  • LSM Bio
  • 进口
  • PAab09183
  • 2025年07月15日
  • ELISA,WB,IHC,FC,IP
  • E. coli - derived recombinant protein
  • Human,Mouse ,Rat
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      ubiquitin-conjugating enzyme E2S

    • 亚型

      IgG

    • 形态

      liquid

    • 保存条件

      负20摄氏度

    • 克隆性

      Polyclonal antibody

    • 标记物

      Non-conjugated

    • 适应物种

      Human,Mouse ,Rat

    • 保质期

      6个月

    • 抗原来源

      Rabbit

    • 目录编号

      Q9BZJ3

    • 级别

      纯化级别

    • 库存

      50

    • 供应商

      LSM bio

    • 宿主

      E. coli - derived recombinant protein

    • 应用范围

      ELISA,WB,IHC,FC,IP

    • 浓度

      ≥95% as determined by SDS-PAGE

    • 靶点

      ubiquitin-conjugating enzyme E2S

    • 抗体英文名

      anti-UBE2S antibody,UBE2S antibody

    • 抗体名

      anti-UBE2S 抗体,UBE2S 抗体

    • 规格

      100μl

    UBE2S抗体| UBE2S antibody

    货号   PAab09183

    蛋白别名   E2 EPF antibody, E2EPF antibody, EPF5 antibody, UBE2S antibody, Ubiquitin carrier protein S antibody, Ubiquitin protein ligase S

    蛋白介绍

    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as a E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except 'Lys-48'-linked polyubiquitination.


    产品描述

    anti-UBE2S antibody is a Rabbit Polyclonal antibody againstUBE2S..

    建议稀释比例

    WB : 1:200-1:2000;IP:1:500-1:5000;IHC:1:20-1:200


    IHC

    Immunohistochemistry of paraffin-embedded human breast cancer using PAab09183(UBE2S antibody) at dilution of 1:50


    Western blot

    MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with PAab09183(UBE2S antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!) "">  

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    图标文献和实验
    该产品被引用文献
    Chinese Journal of Tissue Engineering Research ›› 2021, Vol. 25 ›› Issue (4): 510-515.doi: 10.3969/j.issn.2095-4344.2361 Decalcified bone matrix and lentivirus-mediated silencing of P75 neurotrophin receptor transfected bone marrow mesenchymal stem cells to construct tissue-engineered boneDOI:10.21037/jtd.2020.03.103
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    UBE2S| UBE2S antibody
    ¥2260