- ￥2260
- LSM Bio
- 进口
- PAab09178
- 2025年07月15日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
- 抗体英文名：
anti-UBE2K antibody,UBE2K antibody
- 抗体名：
anti-UBE2K 抗体,UBE2K 抗体
- 规格：
100μl
UBE2K抗体| UBE2K antibody
货号 PAab09178
蛋白别名 DKFZp564C1216 antibody, DKFZp686J24237 antibody, E2-25K antibody, HIP 2 antibody, HIP2 antibody, HYPG antibody, LIG antibody, UBE2K antibody, Ubiquitin carrier protein antibody, Ubiquitin protein ligase
蛋白介绍
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, in the presence or in the absence of BRCA1-BARD1 E3 ubiquitin-protein ligase complex, catalyzes the synthesis of 'Lys-48'-linked polyubiquitin chains. Does not transfer ubiquitin directly to but elongates monoubiquitinated substrate protein. Mediates the selective degradation of short-lived and abnormal proteins, such as the endoplasmic reticulum-associated degradation (ERAD) of misfolded lumenal proteins. Ubiquitinates huntingtin. May mediate foam cell formation by the suppression of apoptosis of lipid-bearing macrophages through ubiquitination and subsequence degradation of p53/TP53. Proposed to be involved in ubiquitination and proteolytic processing of NF-kappa-B; in vitro supports ubiquitination of NFKB1. In case of infection by cytomegaloviruses may be involved in the US11-dependent degradation of MHC class I heavy chains following their export from the ER to the cytosol. In case of viral infections may be involved in the HPV E7 protein- dependent degradation of RB1.
产品描述
anti-UBE2K antibody is a Rabbit Polyclonal antibody againstUBE2K..
建议稀释比例
WB : 1:500-1:5000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human gliomas using PAab09178(UBE2K antibody) at dilution of 1:50
Western blot
human brain tissue were subjected to SDS PAGE followed by western blot with PAab09178(UBE2K antibody) at dilution of 1:400(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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