- ￥2262
- LSM Bio
- 进口
- PAab08893
- 2025年07月15日
- ELISA,WB,IHC,IF
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
thiopurine S-methyltransferase
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
thiopurine S-methyltransferase
- 抗体英文名：
anti-TPMT antibody,TPMT antibody
- 抗体名：
anti-TPMT 抗体,TPMT 抗体
- 规格：
100μg
TPMT抗体| TPMT antibody
货号 PAab08893
蛋白别名
蛋白介绍
Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine.
产品描述
anti-TPMT antibody is a Rabbit Polyclonal antibody againstTPMT..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human lung cancer using PAab08893(TPMT antibody) at dilution of 1:100
Western blot
human kidney tissue were subjected to SDS PAGE followed by western blot with PAab08893(TPMT antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验Thiopurine S-Methyltransferase Pharmacogenetics in Childhood Acute Lymphoblastic Leukemia
in the thiopurine S-methyltransferase gene (TPMT ), the predominant inactivating enzyme for thiopurines in hematopoietic tissue, are correlated with enzymatic activity of TPMT, thiopurine metabolism, and risk of clinical toxicity. In this chapter, we present TPMT
Pharmacogenomics of Drug-Metabolizing Enzymes and Drug Transporters in Chemotherapy
methyltransferase (TPMT), UGT (uridine diphosphate glucuronosyltransferase) 1A1*28, and DPD (dihydropyrimidine dehydrogenase) *2A, respectively, for 6-mercaptopurine, irinotecan, and 5-fluorouracil therapy. However, in most other anticancer therapies no clear
：BRCA1，BRCA2，MSH2，MLH1，DMD，APC，SMA，NF1，NF2，VHL，TSC1/2，MECP2，NSD1，LDLR，FBN1，CFTR，DPYD，COOL5A1，CACNA1A，PKHD1，BRIP1，SLC26A4，LNM1B，PRSS1，FRMD7，TPMT，FLCN，DNAI1，EP300，DNAH5，UBE3A，PCCA，PCDH15等。 2.检测大范围的染色体重排：williams syndrome，prader-willi/angelman syndrome
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