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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
SLIT-ROBO Rho GTPase activating protein 2
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
SLIT-ROBO Rho GTPase activating protein 2
- 抗体英文名:
anti-SRGAP2 antibody,SRGAP2 antibody
- 抗体名:
anti-SRGAP2 抗体,SRGAP2 抗体
- 规格:
100μg
SRGAP2抗体| SRGAP2 antibody
货号 PAab08225
蛋白别名 ARHGAP34 antibody, FNBP2 antibody, Formin binding protein 2 antibody, KIAA0456 antibody, SRGAP2 antibody, srGAP3
蛋白介绍
RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex. Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation, alters dendritic spine morphology and density and indirectly increases neuronal migration. It may have implications for cognition, learning and memory. In non-neuronal cells, it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia.
产品描述
anti-SRGAP2 antibody is a Rabbit Polyclonal antibody againstSRGAP2..
建议稀释比例
WB : 1:500-1:5000 IP : 1:500-1:5000 IHC : 1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human kidney slide using PAab08225( SRGAP2 Antibody) at dilution of 1:50
Western blot
mouse kidney tissue were subjected to SDS PAGE followed by western blot with PAab08225(SRGAP2 antibody) at dilution of 1:1000(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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