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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Rho GDP dissociation inhibitor (GDI) alpha
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
Rho GDP dissociation inhibitor (GDI) alpha
- 抗体英文名:
anti-RhoGDI antibody,RhoGDI antibody
- 抗体名:
anti-RhoGDI 抗体,RhoGDI 抗体
- 规格:
100μg
RhoGDI抗体| RhoGDI antibody
货号 PAab07286
蛋白别名 AGDI antibody, ARHGDIA antibody, GDIA1 antibody, Rho GDI 1 antibody, Rho GDI alpha antibody, RHOGDI antibody, RHOGDI 1
蛋白介绍
Aplysia Ras-related homologs (ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA (also called Rho GDP-dissociation inhibitor 1, Rho GDI1). Rho GDI1 acts as a metastasis-related protein in colon and prostate cancer patients and may be useful as a diagnostic biomarker to prevent colon and prostate cancer metastasis.
产品描述
anti-RhoGDI antibody is a Rabbit Polyclonal antibody againstRhoGDI..
建议稀释比例
WB:1:500-1:5000;IHC:1:20-1:200
IHC
Immunohistochemistry of paraffin-embedded human breast cancer using PAab07286(ARHGDIA,aGDI antibody) at dilution of 1:50
Western blot
Jurkat cells were subjected to SDS PAGE followed by western blot with PAab07286(ARHGDIA,aGDI antibody) at dilution of 1:1000(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验Analysis of the Role of RhoGDI1 and Isoprenylation in the Degradation of RhoGTPases
RhoGDI1 is one of the three major regulators of the Rho switch along with RhoGEFs and RhoGAPs. RhoGDI1 extracts prenylated Rho proteins from lipid membranes, sequesters them in the cytosol, and prevents nucleotide exchange or hydrolysis
Tight regulation of Rho GTPase-signaling functions requires the proper localization of proteins to the membrane and cytosolic compartments, which can themselves undergo reconfiguration in response to signaling events. The importance of lipid
【求助】谁有兔抗Paxillin和鼠抗phorsphotyrosine
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