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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
radical S-adenosyl methionine domain containing 2
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IF,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
radical S-adenosyl methionine domain containing 2
- 抗体英文名:
anti-RSAD2 antibody,RSAD2 antibody
- 抗体名:
anti-RSAD2 抗体,RSAD2 抗体
- 规格:
100μg
RSAD2抗体| RSAD2 antibody
货号 PAab07504
蛋白别名 CIG5
蛋白介绍
Interferon-inducible iron-sulfur (4FE-4S) cluster- binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of DNA and RNA viruses, including human cytomegalovirus (HCMV), hepatitis C virus (HCV), west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus, vesicular stomatitis virus (VSV), and human immunodeficiency virus (HIV-1). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, through binding and inhibition of the enzyme farnesyl diphospate synthase (FPPS), which is essential for the biosynthesis of isoprenoid-derived lipids. Promotes TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating Lys-63'-linked ubiquitination of IRAK1. Plays a role in CD4+ T-cells activation and differentiation. Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities. Can inhibit secretion of soluble proteins.
产品描述
anti-RSAD2 antibody is a Rabbit Polyclonal antibody againstRSAD2..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human skin using PAab07504(RSAD2 antibody) at dilution of 1:50
Western blot
A549 cells were subjected to SDS PAGE followed by western blot with PAab07504(RSAD2 antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验
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