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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
ring finger protein 40
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
ring finger protein 40
- 抗体英文名:
anti-RNF40 antibody,RNF40 antibody
- 抗体名:
anti-RNF40 抗体,RNF40 抗体
- 规格:
100μg
RNF40抗体| RNF40 antibody
货号 PAab07358
蛋白别名 BRE1B antibody, KIAA0661
蛋白介绍
Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.
产品描述
anti-RNF40 antibody is a Rabbit Polyclonal antibody againstRNF40..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验B:Bre1(酵母)及其同系物 RNF20/RNF40(哺乳动物) 多聚泛素化 H2A/H2AX K63:RNF8/RNF168 组蛋白修饰快速参考指南 最常见的组蛋白修饰及发现位置: 组蛋白修饰 功能 位点 H3K4me1 活化 增强子 H3K4me3 活化
25, CYP4F8, RPS6KA3, FBLN1, RASSF5, PHF19, CDH15, ARSA, SCN4B, SUMF2, ZNF763, ALKBH3, RNF40 120 2.9910 0.03602 hsa-miR-1260b GO:0051252:regulation of RNA metabolic process ZNF583, SNIP
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