- ￥2262
- LSM Bio
- 进口
- PAab07120
- 2025年07月15日
- ELISA
- E. coli - derived recombinant protein
- Human, Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
retinoic acid receptor, alpha
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
retinoic acid receptor, alpha
- 抗体英文名：
anti-RARA antibody,RARA antibody
- 抗体名：
anti-RARA 抗体,RARA 抗体
- 规格：
100μg
RARA抗体| RARA antibody
货号 PAab07120
蛋白别名 NR1B1
蛋白介绍
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, the RXR-RAR heterodimers associate with a multiprotein complex containing transcription corepressors that induce histone acetylation, chromatin condensation and transcriptional suppression. On ligand binding, the corepressors dissociate from the receptors and associate with the coactivators leading to transcriptional activation. RARA plays an essential role in the regulation of retinoic acid-induced germ cell development during spermatogenesis. Has a role in the survival of early spermatocytes at the beginning prophase of meiosis. In Sertoli cells, may promote the survival and development of early meiotic prophase spermatocytes. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). Regulates expression of target genes in a ligand- dependent manner by recruiting chromatin complexes containing KMT2E/MLL5. Mediates retinoic acid-induced granulopoiesis.
产品描述
anti-RARA antibody is a Rabbit Polyclonal antibody againstRARA..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验Quantitative Assessment of PML-RARa and BCR-ABL by Two Real-Time PCR Instruments
由多个实验室参与、Roche赞助的、研究LigntCycler和ABI PRISM real-time PCR仪性能对比的论文，发表在2004年Clinical Chemistry上（2004;50:1088-1092），SCI IF 5.454 点击下载 a and BCR-ABL by Two Real-Time PCR Instruments.pdf
Diagnosis and Monitoring of PML-RARA-Positive Acute Promyelocytic Leukemia by Qualitative RT-PCR
The t(15;17) is the diagnostic hallmark of acute promyelocytic leukemia (APL). As a result, the RARA and the promyelocytic leukemia (PML) genes are fused. The use of reverse-transcription polymerase chain reaction (RT-PCR) for the detection
曾经在水一方 请教各位大侠，如何查找融合基因的mRNA序列？比如说PML/RARA，可以利用Map viewer 分别查出PML和RARA的mRNA序列，然后在融合位点拼接吗？有什么可用的方法，请大家帮我推荐一下。谢谢了 bingbing6612 这是问题吗？学过分子生物学的都知道 曾经在水一方 让您见笑了。还请您不吝赐教。 本文由丁香园论坛提供，想了解更多有用的、有意
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