- ￥2262
- LSM Bio
- 进口
- PAab07079
- 2025年07月15日
- ELISA,WB,IP
- E. coli - derived recombinant protein
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
- 抗体英文名：
anti-RAD51 antibody,RAD51 antibody
- 抗体名：
anti-RAD51 抗体,RAD51 抗体
- 规格：
100μg
RAD51抗体| RAD51 antibody
货号 PAab07079
蛋白别名 RAD51A antibody, RECA
蛋白介绍
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
产品描述
anti-RAD51 antibody is a Rabbit Polyclonal antibody againstRAD51..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验Biochemical Studies on Human Rad51-Mediated Homologous Recombination
Rad51-mediated pairing between homologous DNA sequences during homologous recombination (HR) plays pivotal roles in DNA double-strand break repair. The multi-step process occurs through cooperation of Rad51 and a number of accessory protein
Assay for Human Rad51-Mediated DNA Displacement Loop Formation
同源重组（Homologus Recombination) 是指发生在姐妹染色单体（sister chromatin) 之间或同一染色体上含有同源序列的DNA分子之间或分子之内的重新组合。同源重组需要一系列的蛋白质催化，如原核生物细胞内的RecA、RecBCD、RecF、RecO、RecR等；以及真核生物细胞内的Rad51、Mre11-Rad50等等。 在人类细胞中，同源重组由Rad51介导，在有ATP的条件下，Rad51聚合在单链DNA上，形成一个核蛋白
In Vitro Assays for DNA Pairing and Recombination-Associated DNA Synthesis
/Rad51 family of proteins are the key enzymes in this homology-directed repair pathway, as they perform DNA strand invasion and exchange, in concert with a host of ancillary factors. In vitro, the RecA/Rad51 family of proteins share similar enzymatic
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