- ￥2262
- LSM Bio
- 进口
- PAab07038
- 2025年07月15日
- ELISA,IHC,WB,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
RAB5A, member RAS oncogene family
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IHC,WB,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
RAB5A, member RAS oncogene family
- 抗体英文名：
anti-RAB5A antibody,RAB5A antibody
- 抗体名：
anti-RAB5A 抗体,RAB5A 抗体
- 规格：
100μg
RAB5A抗体| RAB5A antibody
货号 PAab07038
蛋白别名 RAB5
蛋白介绍
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes (PubMed:10818110, PubMed:14617813, PubMed:16410077, PubMed:15378032). Contributes to the regulation of filopodia extension (PubMed:14978216). Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan (PubMed:22660413). Regulates maturation of apoptotic cell- containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity).
产品描述
anti-RAB5A antibody is a Rabbit Polyclonal antibody againstRAB5A..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using PAab07038( RAB5A Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab07038(RAB5A antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验Segmental and Subcellular Distribution of CFTR in the Kidney
, Rab5a. Deglycosylation studies and immunoblotting show a distinct glycosylation pattern for CFTR in mouse kidney and lung. The segmental and subcellular distribution of CFTR in mouse kidney supports a role for CFTR in PT receptor-mediated endocytosis
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