- ￥2262
- LSM Bio
- 进口
- PAab06903
- 2025年07月15日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
proline-serine-threonine phosphatase interacting protein 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
proline-serine-threonine phosphatase interacting protein 1
- 抗体英文名：
anti-PSTPIP1 antibody,PSTPIP1 antibody
- 抗体名：
anti-PSTPIP1 抗体,PSTPIP1 抗体
- 规格：
100μg
PSTPIP1抗体| PSTPIP1 antibody
货号 PAab06903
蛋白别名 CD2BP1
蛋白介绍
Involved in regulation of the actin cytoskeleton. May regulate WAS actin-bundling activity. Bridges the interaction between ABL1 and PTPN18 leading to ABL1 dephosphorylation. May play a role as a scaffold protein between PTPN12 and WAS and allow PTPN12 to dephosphorylate WAS. Has the potential to physically couple CD2 and CD2AP to WAS. Acts downstream of CD2 and CD2AP to recruit WAS to the T-cell:APC contact site so as to promote the actin polymerization required for synapse induction during T-cell activation (By similarity). Down-regulates CD2-stimulated adhesion through the coupling of PTPN12 to CD2. Also has a role in innate immunity and the inflammatory response. Recruited to inflammasomes by MEFV. Induces formation of pyroptosomes, large supramolecular structures composed of oligomerized PYCARD dimers which form prior to inflammatory apoptosis. Binding to MEFV allows MEFV to bind to PYCARD and facilitates pyroptosome formation. Regulates endocytosis and cell migration in neutrophils.
产品描述
anti-PSTPIP1 antibody is a Rabbit Polyclonal antibody againstPSTPIP1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human brain using PAab06903(PSTPIP1 antibody) at dilution of 1:50
Western blot
mouse thymus tissue were subjected to SDS PAGE followed by western blot with PAab06903(PSTPIP1 antibody) at dilution of 1:300(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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