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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
proteasome (prosome, macropain) subunit, alpha type, 7
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,FC,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
proteasome (prosome, macropain) subunit, alpha type, 7
- 抗体英文名:
anti-PSMA7 antibody,PSMA7 antibody
- 抗体名:
anti-PSMA7 抗体,PSMA7 抗体
- 规格:
100μg
PSMA7抗体| PSMA7 antibody
货号 PAab06866
蛋白别名 HSPC
蛋白介绍
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
产品描述
anti-PSMA7 antibody is a Rabbit Polyclonal antibody againstPSMA7..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human liver cancer using PAab06866(PSMA7 antibody) at dilution of 1:50
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab06866(PSMA7 antibody) at dilution of 1:1000(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
Homo sapiens cathepsin D (lysosomal aspartyl protease) (CTSD), mRNA 1512 NM_002792 Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 7 (PSMA7), transcript variant 1, mRNA 728 NM_002799 Homo sapiens proteasome (prosome, macropain
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