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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
polyglutamine binding protein 1
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
polyglutamine binding protein 1
- 抗体英文名:
anti-PQBP1 antibody,PQBP1 antibody
- 抗体名:
anti-PQBP1 抗体,PQBP1 抗体
- 规格:
100μg
PQBP1抗体| PQBP1 antibody
货号 PAab06743
蛋白别名 NPW38
蛋白介绍
Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species (PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
产品描述
anti-PQBP1 antibody is a Rabbit Polyclonal antibody againstPQBP1..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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文献和实验【共享】某机构发表的核酸相关研究的文章(EST,SNP等),PDF全文下载
Truncating Mutations in the Polyglutamine Tract Binding Protein 1 Gene (PQBP1) Cause Renpenning Syndrome and X-Linked Mental Retardation in Another Family with Microcephaly Am J Hum Genet 74: 777-780 pdf Piel J, Hui D, Wen G, Butzke D, Platzer M, Fusetani
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