- ￥2262
- LSM Bio
- 进口
- PAab06735
- 2025年07月14日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human, Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
protein phosphatase 5, catalytic subunit
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
protein phosphatase 5, catalytic subunit
- 抗体英文名：
anti-PPP5C antibody,PPP5C antibody
- 抗体名：
anti-PPP5C 抗体,PPP5C 抗体
- 规格：
100μg
PPP5C抗体| PPP5C antibody
货号 PAab06735
蛋白别名 PPP5
蛋白介绍
Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT. Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses. Participates in the control of DNA damage response mechanisms such as checkpoint activation and DNA damage repair through, for instance, the regulation ATM/ATR-signaling and dephosphorylation of PRKDC and TP53BP1. Inhibits ASK1/MAP3K5-mediated apoptosis induced by oxidative stress. Plays a positive role in adipogenesis, mainly through the dephosphorylation and activation of PPARG transactivation function. Also dephosphorylates and inhibits the anti-adipogenic effect of NR3C1. Regulates the circadian rhythms, through the dephosphorylation and activation of CSNK1E. May modulate TGF-beta signaling pathway by the regulation of SMAD3 phosphorylation and protein expression levels. Dephosphorylates and may play a role in the regulation of TAU/MAPT. Through their dephosphorylation, may play a role in the regulation of ions channels such as KCNH2.
产品描述
anti-PPP5C antibody is a Rabbit Polyclonal antibody againstPPP5C..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human gliomas using PAab06735(PPP5C antibody) at dilution of 1:100
Western blot
mouse testis tissue were subjected to SDS PAGE followed by western blot with PAab06735(PPP5C antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验AP6804a MTMR4 C-term Antibody AP8463a PPP4C N-term Antibody AP8441b DUSP10 C-term Antibody AP6805a MTMR5 N-term Antibody AP8464a PPP5C Center Antibody AP8441a DUSP10 N-term Antibody AP6806a MTMR6 C-term Antibody AP8464b PPP5C C-term
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