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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
protein phosphatase 4, regulatory subunit 2
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
protein phosphatase 4, regulatory subunit 2
- 抗体英文名:
anti-PPP4R2 antibody,PPP4R2 antibody
- 抗体名:
anti-PPP4R2 抗体,PPP4R2 抗体
- 规格:
100μg
PPP4R2抗体| PPP4R2 antibody
货号 PAab06734
蛋白别名
蛋白介绍
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair.
产品描述
anti-PPP4R2 antibody is a Rabbit Polyclonal antibody againstPPP4R2..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using PAab06734( PPP4R2 Antibody) at dilution of 1:50
Western blot
A549 cells were subjected to SDS PAGE followed by western blot with PAab06734(PPP4R2 antibody) at dilution of 1:1000(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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