- ￥2262
- LSM Bio
- 进口
- PAab06733
- 2025年07月15日
- ELISA,WB,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
protein phosphatase 4 (formerly X), catalytic subunit
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
protein phosphatase 4 (formerly X), catalytic subunit
- 抗体英文名：
anti-PPP4C antibody,PPP4C antibody
- 抗体名：
anti-PPP4C 抗体,PPP4C 抗体
- 规格：
100μg
PPP4C抗体| PPP4C antibody
货号 PAab06733
蛋白别名 PPP4 antibody, PPX
蛋白介绍
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C- PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
产品描述
anti-PPP4C antibody is a Rabbit Polyclonal antibody againstPPP4C..
建议稀释比例
IHC
Western blot
(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验PPP3CC C-term Antibody AP8402a DEP1 C-term Antibody AP6802a MTMR2 N-term Antibody AP8453a PPP3CC N-term Antibody AP8433b DUSP1 C-term Antibody AP6803a MTMR3 C-term Antibody AP8463b PPP4C C-term Antibody AP8433a DUSP1 N-term Antibody
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