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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
protein phosphatase 1, regulatory (inhibitor) subunit 9B
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
P67936
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
protein phosphatase 1, regulatory (inhibitor) subunit 9B
- 抗体英文名:
anti-PPP1R9B antibody,PPP1R9B antibody
- 抗体名:
anti-PPP1R9B 抗体,PPP1R9B 抗体
- 规格:
100μg
PPP1R9B抗体| PPP1R9B antibody
货号 PAab06711
蛋白别名 PPP1R6
蛋白介绍
Seems to act as a scaffold protein in multiple signaling pathways. Modulates excitatory synaptic transmission and dendritic spine morphology. Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction. Believed to target protein phosphatase 1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity toward ion channels and other substrates, such as AMPA-type and NMDA-type glutamate receptors. Plays a role in regulation of G-protein coupled receptor signaling, including dopamine D2 receptors and alpha- adrenergic receptors. May establish a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B signaling. May confer to Rac signaling specificity by binding to both, RacGEFs and Rac effector proteins. Probably regulates p70 S6 kinase activity by forming a complex with TIAM1 (By similarity). Required for hepatocyte growth factor (HGF)- induced cell migration.
产品描述
anti-PPP1R9B antibody is a Rabbit Polyclonal antibody againstPPP1R9B..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human brain using PAab06711(PPP1R9B antibody) at dilution of 1:50
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab06711(PPP1R9B antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!) "">
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