- ￥2262
- LSM Bio
- 进口
- PAab06569
- 2025年07月15日
- ELISA,WB,IHC,IF
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
prostate transmembrane protein, androgen induced 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P67936
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
prostate transmembrane protein, androgen induced 1
- 抗体英文名：
anti-PMEPA1 antibody,PMEPA1 antibody
- 抗体名：
anti-PMEPA1 抗体,PMEPA1 抗体
- 规格：
100μg
PMEPA1抗体| PMEPA1 antibody
货号 PAab06569
蛋白别名 STAG1 antibody, TMEPAI
蛋白介绍
Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal (PubMed:20129061, PubMed:24627487). Also involved in down-regulation of the androgen receptor (AR), enhancing ubiquitination and proteasome-mediated degradation of AR, probably by recruiting NEDD4 (PubMed:18703514).
产品描述
anti-PMEPA1 antibody is a Rabbit Polyclonal antibody againstPMEPA1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human prostate hyperplasia using PAab06569(PMEPA1 antibody) at dilution of 1:50
Western blot
L02 cells were subjected to SDS PAGE followed by western blot with PAab06569( PMEPA1 Antibody) at dilution of 1:600(本抗体仅供体外科研用途，不可用于临床诊断!) "">
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文献和实验
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