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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
nucleoporin 85kDa
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9WVH4
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IF
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
nucleoporin 85kDa
- 抗体英文名:
anti-NUP85 antibody,NUP85 antibody
- 抗体名:
anti-NUP85 抗体,NUP85 抗体
- 规格:
100μl
NUP85抗体| NUP85 antibody
货号 PAab05929
蛋白别名 NUP75 antibody, PCNT1
蛋白介绍
Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2- activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl- inositol 3-kinase-Rac-lammellipodium protrusion cascade.
产品描述
anti-NUP85 antibody is a Rabbit Polyclonal antibody againstNUP85..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human stomach using PAab05929(NUP85 antibody) at dilution of 1:50
Western blot
mouse lung tissue were subjected to SDS PAGE followed by western blot with PAab05929(NUP85 antibody) at dilution of 1:400(本抗体仅供体外科研用途,不可用于临床诊断!) <"">
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文献和实验施一公团队突破性进展再登 Science!以超高分辨率解析核孔复合物的结构细节
Y 复合物。CR 中的 16 个 Y 复合体,8 个内部和 8 个外部 Y 复合体,以头到尾的方式组装,以近端和远端同心的形式构建支架。Y 复合体由短臂(Nup85、Nup43 和 Seh1)、长臂(Nup160 和 Nup37)和茎(Nup96、Sec13、Nup107 和 Nup133)组成。 随后,本研究继续将步伐迈向了探索其细节的过程,鉴定了 Nup358、Nup205 和 Nup93 是 CR 支架的组成部分,CR 亚单位模型包含 30 个核孔蛋白中的 19037 个氨
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