- ￥2262
- LSM Bio
- 进口
- PAab05917
- 2025年07月15日
- ELISA,IF,WB,IHC,IP
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
numb homolog (Drosophila)-like
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,IF,WB,IHC,IP
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
numb homolog (Drosophila)-like
- 抗体英文名：
anti-NUMBL antibody,NUMBL antibody
- 抗体名：
anti-NUMBL 抗体,NUMBL 抗体
- 规格：
100μl
NUMBL抗体| NUMBL antibody
货号 PAab05917
蛋白别名
蛋白介绍
Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF- kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.
产品描述
anti-NUMBL antibody is a Rabbit Polyclonal antibody againstNUMBL..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human gliomas tissue slide using PAab05917( NUMBLIKE Antibody) at dilution of 1:50
Western blot
mouse brain tissue were subjected to SDS PAGE followed by western blot with PAab05917( NUMBLIKE Antibody) at dilution of 1:2000(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验
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