- ￥2650
- LSM Bio
- 进口
- PAab05767
- 2025年07月15日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
nicotinamide nucleotide adenylyltransferase 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
nicotinamide nucleotide adenylyltransferase 1
- 抗体英文名：
anti-NMNAT1 antibody,NMNAT1 antibody
- 抗体名：
anti-NMNAT1 抗体,NMNAT1 抗体
- 规格：
100μl
NMNAT1抗体| NMNAT1 antibody
货号 PAab05767
蛋白别名 NMNAT
蛋白介绍
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP (PubMed:17402747). Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency (PubMed:17402747). Can use triazofurin monophosphate (TrMP) as substrate (PubMed:17402747). Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+) (PubMed:17402747). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively (PubMed:17402747). Involved in the synthesis of ATP in the nucleus, together with PARP1, PARG and NUDT5 (PubMed:27257257). Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming (PubMed:27257257). Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+) (PubMed:17402747). Protects against axonal degeneration following mechanical or toxic insults (By similarity).
产品描述
anti-NMNAT1 antibody is a Rabbit Polyclonal antibody againstNMNAT1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human pancreas cancer using PAab05767(NMNAT1 antibody) at dilution of 1:50
Western blot
human testis tissue were subjected to SDS PAGE followed by western blot with PAab05767(NMNAT1 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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