- ￥2650
- LSM Bio
- 进口
- PAab05726
- 2025年07月16日
- ELISA,WB,IHC
- E. coli - derived recombinant protein
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
NHL repeat containing 1
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
Q9WVH4
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
NHL repeat containing 1
- 抗体英文名：
anti-NHLRC1 antibody,NHLRC1 antibody
- 抗体名：
anti-NHLRC1 抗体,NHLRC1 抗体
- 规格：
100μl
NHLRC1抗体| NHLRC1 antibody
货号 PAab05726
蛋白别名 EPM2B
蛋白介绍
E3 ubiquitin-protein ligase. Together with the phosphatase EPM2A/laforin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. In complex with EPM2A/laforin and HSP70, suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system (UPS). Ubiquitinates the glycogen-targeting protein phosphatase subunits PPP1R3C/PTG and PPP1R3D in a laforin-dependent manner and targets them for proteasome-dependent degradation, thus decreasing glycogen accumulation. Polyubiquitinates EPM2A/laforin and ubiquitinates AGL and targets them for proteasome-dependent degradation. Also promotes proteasome-independent protein degradation through the macroautophagy pathway.
产品描述
anti-NHLRC1 antibody is a Rabbit Polyclonal antibody againstNHLRC1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human heart using PAab05726(NHLRC1 antibody) at dilution of 1:50
Western blot
L02 cells were subjected to SDS PAGE followed by western blot with PAab05726(NHLRC1 antibody) at dilution of 1:400(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验
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