- ￥2262
- LSM Bio
- 进口
- PAab03533
- 2025年07月15日
- ELISA,WB,IHC,IF
- E. coli - derived recombinant protein
- Human,Mouse ,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
- 亚型：
IgG
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
Polyclonal antibody
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse ,Rat
- 保质期：
6个月
- 抗原来源：
Rabbit
- 目录编号：
P15248
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA,WB,IHC,IF
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
- 抗体英文名：
anti-GNAI3 antibody,GNAI3 antibody
- 抗体名：
anti-GNAI3 抗体,GNAI3 抗体
- 规格：
100μg
GNAI3抗体| GNAI3 antibody
货号 PAab03533
蛋白别名
蛋白介绍
Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins (PubMed:8774883, PubMed:18434541, PubMed:19478087). Signaling is mediated via effector proteins, such as adenylate cyclase. Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels (PubMed:19478087). Stimulates the activity of receptor-regulated K(+) channels (PubMed:2535845). The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division (PubMed:17635935).
产品描述
anti-GNAI3 antibody is a Rabbit Polyclonal antibody againstGNAI3..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human kidney using PAab03533(GNAI3 antibody) at dilution of 1:50
Western blot
mouse kidney tissue were subjected to SDS PAGE followed by western blot with PAab03533(GNAI3 antibody) at dilution of 1:500(本抗体仅供体外科研用途，不可用于临床诊断!) <"">
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文献和实验
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