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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
dynein, light chain, Tctex-type 1
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
DYNLT1
- 抗体英文名:
anti-DYNLT1 antibody,DYNLT1 antibody
- 抗体名:
anti-DYNLT1 抗体,DYNLT1 抗体
- 规格:
100μg
DYNLT1抗体| DYNLT1 antibody
货号 PAab02590
蛋白别名 TCTEL1 antibody, TCTEX-1 antibody, TCTEX1
蛋白介绍
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Binds to transport cargos and is involved in apical cargo transport such as rhodopsin-bearing vesicles in polarized epithelia. Is involved in intracellular targeting of D-type retrovirus gag polyproteins to the cytoplasmic assembly site. May also be a accessory component of axonemal dynein. Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity. The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer. May function as a receptor- independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange. Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2. Involved in the regulation of mitotic spindle orientation (By similarity).
产品描述
anti-DYNLT1 antibody is a Rabbit Polyclonal antibody againstDYNLT1..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human pancreas using PAab02590(DYNLT1 antibody) at dilution of 1:50
Western blot
human brain tissue were subjected to SDS PAGE followed by western blot with PAab02590(DYNLT1 antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!)
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