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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
coxsackie virus and adenovirus receptor
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
CXADR
- 抗体英文名:
anti-CXADR antibody,CXADR antibody
- 抗体名:
anti-CXADR 抗体,CXADR 抗体
- 规格:
100μg
CXADR抗体| CXADR antibody
货号 PAab02091
蛋白别名 CAR
蛋白介绍
Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. (Microbial infection) Acts as a receptor for adenovirus type C (PubMed:9733828, PubMed:10666333, PubMed:12297051, PubMed:10567268). Acts as a receptor for Coxsackievirus B1 to B6 (PubMed:14978041, PubMed:10814575).
产品描述
anti-CXADR antibody is a Rabbit Polyclonal antibody againstCXADR..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human breast cancer using PAab02091(CXADR antibody) at dilution of 1:50
Western blot
BxPC-3 cells were subjected to SDS PAGE followed by western blot with PAab02091(CXADR antibody) at dilution of 1:500(本抗体仅供体外科研用途,不可用于临床诊断!)
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文献和实验
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