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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
COPS7A
- 抗体英文名:
anti-COPS7A antibody,COPS7A antibody
- 抗体名:
anti-COPS7A 抗体,COPS7A 抗体
- 规格:
100μg
COPS7A抗体| COPS7A antibody
货号 PAab01873
蛋白别名 CSN7A antibody, DERP10
蛋白介绍
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
产品描述
anti-COPS7A antibody is a Rabbit Polyclonal antibody againstCOPS7A..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human kidney using PAab01873(COPS7A antibody) at dilution of 1:50
Western blot
human heart tissue were subjected to SDS PAGE followed by western blot with PAab01873(COPS7A antibody) at dilution of 1:300(本抗体仅供体外科研用途,不可用于临床诊断!)
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文献和实验
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