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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
chromatin modifying protein 1B
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
Polyclonal antibody
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse ,Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9GZT9
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA,WB,IHC,IP
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
CHMP1B
- 抗体英文名:
anti-CHMP1B antibody,CHMP1B antibody
- 抗体名:
anti-CHMP1B 抗体,CHMP1B 抗体
- 规格:
100μg
CHMP1B抗体| CHMP1B antibody
货号 PAab01657
蛋白别名 C18orf2
蛋白介绍
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT- III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.
产品描述
anti-CHMP1B antibody is a Rabbit Polyclonal antibody againstCHMP1B..
建议稀释比例
IHC
Immunohistochemistry of paraffin-embedded human kidney using PAab01657(CHMP1B antibody) at dilution of 1:50
Western blot
HeLa cells were subjected to SDS PAGE followed by western blot with PAab01657(CHMP1B antibody) at dilution of 1:300(本抗体仅供体外科研用途,不可用于临床诊断!)
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文献和实验
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