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- 详细信息
- 技术资料
- 免疫原:
A phospho specific peptide corresponding to residues surrounding T918 of human MAP3K5
- 亚型:
IgG
- 保存条件:
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性:
单克隆
- 适应物种:
Human Mouse Rat
- 目录编号:
K006190P
- 库存:
999
- 供应商:
北京索莱宝科技有限公司
- 宿主:
Rabbit
- 靶点:
Phospho-MAP3K5-T918
- 抗体英文名:
Anti-Phospho-MAP3K5-T918 Polyclonal Antibody
- 抗体名:
ASK1;MAPKKK5;MEKK5
- 规格:
50ul/100ul
| 规格: | 50ul | 产品价格: | ¥2650.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥4150.0 |
产品简介
| 单位 | 支 |
| 别名 | Dual specificity mitogen activated protein kinase kinase 5, Dual specificity mitogen-activated protein kinase kinase 5, EC 2.7.12.2, HsT17454, MAP kinase kinase 5, MAP kinase kinase MEK5b, MAP2K5, MAPK/ERK kinase 5, MAPKK 5, MAPKK5, MEK 5, mitogen-activated protein kinase kinase 5, MKK5, MP2K5_HUMAN, PRKMK5, Protein kinase, mitogen-activated, kinase 5, SAPKK5, SKK5 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. |
| Gene ID | 4217 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q99683 |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 蛋白分子量 | 70/154kDa |
| 亚细胞定位 | Cytoplasm Endoplasmic reticulum |
| 免疫原 | A phospho specific peptide corresponding to residues surrounding T918 of human MAP3K5 |
| 纯化方法 | Affinity purification |
| 背景资料 | Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK. |
| Public Immunogen Range | A phospho specific peptide corresponding to residues surrounding T918 of human MAP3K5 |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |

实验图
Western blot analysis with Phospho-MAP3K5-T918 antibody diluted at 1:1000
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Anti-Phospho-MAP3K5-T918 Polyclonal Antibody
¥2650 - 4150









