Human Nucleotide-binding oligo

Transmembrane Signaling by Receptor Oligomerization

receptors. The majority of these numerous receptors for growth factors and cytokines are bitopic integral-membrane proteins that contain an extracellular ligand-binding domain; a single transmembrane domain that is assumed to be an α-helix; and a cytoplasmic

Screening Peptide/Protein Libraries Fused to the Repressor DNA-Binding Domain in E. coli Cells

to detect protein-protein interactions in vivo. Protein or peptide targets are fused to the λ repressor DNA binding domain; these fusions can be evaluated for repressor activity using direct selection with λ phage, or a variety of reporter genes suitable

Challenges and Opportunities in Fractionation of Recombinant Human Mannan-Binding Lectin

Mannan-binding lectin is an oligomeric protein of the innate immune system. Both natural MBL as well as recombinant protein is a heterogeneous composition of oligomers containing from two up to at least eight structural units. Recombinant