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文献和实验Genetic Engineering of Live Attenuated Influenza Viruses
The first live attenuated influenza vaccine (LAIV) was licensed in the USA in 2003; it is a trivalent vaccine composed of two type A (H1N1 and H3N2) and one type B influenza virus each at 107 fluorescent focus units (FFU). Each influenza
PCR for the Detection of Influenza Viruses in Clinical Material
Influenza viruses are segmented, negative-stranded RNA viruses belonging to the family Orthomyxoviridae . They are classified into influenza A, B, and C on the basis of different epitopes on the nucleoprotein (NP) and matrix proteins (M
The Pathogenesis of Disease Due to Type b Haemophilus influenzae
Haemophilus influenzae is a Gram-negative bacterium that was first described by Pfeiffer in 1892 (1 ). This ubiquitous, human-specific organism was originally thought to be the etiologic agent of “influenza.” However, H. influenzae
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