- ￥1183
- BioLegend
- 329702
- 美国
- 2025年07月12日
- 免疫荧光，流式
- 小鼠
- Human Reported Reactivity African Green, Baboon, Cynomolgus, Rhesus
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- 技术资料
- 抗体名：
Purified anti-human CD274 (B7-H1, PD-L1)
- 抗体英文名：
Purified anti-human CD274 (B7-H1, PD-L1)
- 浓度：
0.5 mg/mL
- 应用范围：
免疫荧光，流式
- 宿主：
小鼠
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
小鼠
- 保质期：
2-3年左右
- 适应物种：
Human Reported Reactivity African Green, Baboon, Cynomolgus, Rhesus
- 标记物：
Purified
- 克隆性：
单克隆
- 保存条件：
2-8度
- 形态：
液体
- 规格：
100 μg
Purified anti-human CD274 (B7-H1, PD-L1) Antibody
29E.2A3
Catalog# / Size 329701 / 25 µg
329702 / 100 µg
Clone
Regulatory Status RUO
Other Names Programmed cell death ligand 1 (PD-L1), B7 homolog 1 (B7-H1)
Isotype Mouse IgG2b, κ
Description CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a
ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the
stimulatory and inhibitory signals needed for responses to microbes and maintenance of selftolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ
production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that
CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell
activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting
implications for its expression in a wide variety of cell types, including T and B cells, antigenpresenting cells, and nonhematopoietic cells.
Product Details
Verified Reactivity Human
Reported Reactivity African Green, Baboon, Cynomolgus, Rhesus
Antibody Type Monoclonal
Host Species Mouse
Immunogen Full length human PD-L1
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography.
Concentration 0.5 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C.
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