- ￥600 - 1600
- Abbiotec
- 美国
- 300107
- 2025年07月13日
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- 详细信息
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- 技术资料
- 保存条件：
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
- 保质期：
参照说明书可保存1-2年
- 英文名：
TGF-beta Receptor Type II Peptide
- 库存：
一定量库存
- 供应商：
华拓生物
- 规格：
0.1 mg
| 产品名称： | TGF-beta Receptor Type II Peptide |
| 产品链接： | http://www.abbiotec.com/peptides/tgf-beta-receptor-type-ii-peptide |
| 货号： | 300107 |
| 规格： | 0.1 mg |
| 产品描述： | TGF-beta receptor type II (TGFR2) forms a heteromeric complex with TGFR1 after binding TGF-beta at the cell surface and activates TGFR2 by phosphorylation, subsequently binding and activation of the SMAD transcriptional regulators. Defects in TGFR2 are a cause of hereditary non-polyposis colorectal cancer type 6 (HNPCC6), esophageal cancer, and Loeys-Dietz syndromes (aortic aneurism syndrome). |
| 序列： | The synthetic peptide used to raise the antibody Cat. No. 250880 is selected from a sequence within the N-term region of human TGFR2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
| 分子式： | C66H103N17O20 |
| 分子量： | 1454.6 g/mol |
| 纯度： | Purity > 80% by HPLC |
| 别名： | TGF-beta receptor type-2; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TGF-beta type II receptor; TbetaR-II; TGFR-2; TGFBR2 |
| 形态： | Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect. |
| 溶解方法： | Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
| 保存方法： | Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
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文献和实验The Detection of Antibodies to the Angiotensin II-Type 1 Receptor in Transplantation
The detection of auto-antibodies detection is a major aspect of patient’s immunomonitoring. Antibodies directed against the heart and kidney Angiotensin II type 1 receptor (AT1 R) play a major role in antibody mediated rejection after heart
Peptide-Conjugated Quantum Dots: Imaging the Angiotensin Type 1 Receptor in Living Cells
Peptide-quantum dot conjugates have been prepared by attaching angiotensin II (Ang II) to cadmium selenide/zinc sulfide core-shell nanocrystals using an 1-[3-(Dimethyamino)propyl]-3-ethylcarbo diimide hydrochloride (EDC) coupling
Cardiac-Specific Overexpression of Angiotensin II Type 1 Receptor in Transgenic Rats
This chapter describes the methods required for overexpression of the angiotensin II type I receptor (AT1 ) in cardiomyocytes of transgenic rats. This includes cloning of the transgenic construct consisting of the α-myosin heavy chain (MHC
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