4-Hydroxy Atorvastatin-d5 Calc

1) Cat. No.: TRC-H828990; 2) Chemical Name: 4-Hydroxy Atorvastatin-d5 Calcium Salt; 3) CAS No.: ; 4) Mol. Formula: C33H28D5CaFN2O6; 5) Mol. Weight: 617.73; 6) Packing Size: 1mg / 10mg; 7) Appearence: ; 8) Application Notes: A deuterated metabolite of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.; 9) Synonym: (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-4-[[(4-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic Acid-d5 Calcium Salt; p-Hydroxyatorvastatin-d5 Calcium Salt; ; 10) Solubility: ; 11) Storage condition: ; 12) References: Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),