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- 技术资料
- 抗体名:
Purified anti-human CD334 (FGFR4)
- 抗体英文名:
Purified anti-human CD334 (FGFR4)
- 浓度:
0.5 mg/mL
- 应用范围:
免疫荧光,流式
- 宿主:
小鼠
- 供应商:
上海善然生物
- 库存:
4-5周
- 抗原来源:
小鼠
- 保质期:
2-3年左右
- 适应物种:
人
- 标记物:
Purified
- 克隆性:
单克隆
- 保存条件:
2-8度
- 形态:
液体
- 规格:
100 μg
Purified anti-human CD334 (FGFR4) Antibody
4FR6D3
Catalog# / Size 324302 / 100 µg
Clone
Regulatory Status RUO
Other Names FGFR4, fibroblast growth factor receptor 4, TKF, FGF R4
Isotype Mouse IgG1, κ
Description The 4FR6D3 antibody recognizes human CD334, also known as fibroblast growth factor 4,
FGFR4 and TKF. CD334 is a member of the fibroblast growth factor receptor family and a cell
surface tyrosine kinase containing three immunoglobulin-like domains. FGFR4 has a predicted
molecular weight of approximately 88 kD and is widely expressed in many tissues including
the intestine, muscle, heart, cornea, retina, and pancreas, with highest expression in lung and
kidney.CD334 binds acidic fibroblast growth factors (FGF8, GFG1, FGF19, FGF6, and FGF2);
ligand binding induces mitogenesis and differentiation. CD334 has been shown to interact with
STAT1 and STAT3 and is over-expressed in gynecological tumors suggesting a possible role
for this receptor in breast and ovarian tumorigenesis. Unique alleles (Arg388) in FGFR4 have
been shown to be associated with cancer progression and increased tumor cell motility. The
4FR6D3 antibody has been shown to be useful for flow cytometry.
Product Details
Verified Reactivity Human
Antibody Type Monoclonal
Host Species Mouse
Immunogen NIH-3T3 cells transfected with full-length human FGFR4
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography.
Concentration 0.5 mg/mL
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C.
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