- ￥1596
- BioLegend
- 142607
- 美国
- 2026年05月28日
- Armenian Hamster
- 小鼠
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- 技术资料
- 抗体名：
PE/Cyanine7 anti-mouse CD49a
- 抗体英文名：
PE/Cyanine7 anti-mouse CD49a
- 浓度：
0.2 mg/ml
- 宿主：
Armenian Hamster
- 供应商：
上海善然生物
- 库存：
现货
- 抗原来源：
Armenian Hamster
- 保质期：
2-3年左右
- 适应物种：
小鼠
- 标记物：
PE/Cyanine7
- 克隆性：
单克隆
- 保存条件：
2-8度
- 形态：
液体
- 规格：
25ug
PE/Cyanine7 anti-mouse CD49a Antibody
HMα1
Catalog# / Size 142607 / 25 µg
142608 / 100 µg
Clone
Regulatory Status RUO
Other Names Very late antigen 1 (VLA1), integrin alpha 1 (ITGA1)
Isotype Armenian Hamster IgG
Description CD49a is a 1179 aa, type I transmembrane glycoprotein also known as α1 integrin, VLA-1 α
chain, or integrin α1. It associates antibody v042010 with CD29 (β1 integrin) to form the VLA-1
complex, a collagen IV and alminin-1 receptor that is expressed on activated T cells, smooth
muscle cells, endothelial cells, neuronal cells, fibroblasts, and mesenchymal cells. CD49a is
an adhesion molecule and is involved in the regulation of leukocyte migration, T cell
proliferation, and cytokine production.
Product Details
Verified Reactivity Mouse
Antibody Type Monoclonal
Host Species Armenian Hamster
Immunogen Mouse Neuroblastoma Cell Line C1300
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under
optimal conditions.
Concentration 0.2 mg/ml
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.
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ITGA4（CD49D）信号通路、病理作用与靶向治疗药物研究梳理
整合素alpha 4（ITGA4），又称CD49D，是整合素家族的关键亚基。它通过与β1或β7亚基结合，形成功能性异二聚体α4β1（VLA-4）和α4β7，在免疫细胞的黏附、运输及迁移中扮演核心角色。VLA-4还能介导白细胞在活化内皮细胞上的聚集。鉴于ITGA4在多发性硬化、炎症性肠病等多种自身免疫性疾病的病理过程中发挥关键作用，它已成为治疗干预的重要靶点。 ITGA4的表达分布 ITGA4主要分布于巨核细胞、红细胞、干细胞、NK细胞以及T细胞中。在T细胞亚群中，CD49D主要在CD
Characterization of Whole Body Cholesterol Fluxes in the Mouse
in this pathway. This article describes in detail a variety of experimental approaches to measure cholesterol fluxes in the hepatobiliary system as well as in the intestinal pathway. Curr. Protoc. Mouse Biol. 1:413?427 © 2011 by John Wiley & Sons
Immunofluorescent Staining of Mouse and Rat Leukocytes
-up, please see description in "Procedure for Setting Compensation for Multi-Color Flow Cytometric Analysis". For reducing FcgII/IIIR-mediated antibody binding (or binding of SAv-PE or SAv-Cy-Chrome) which could contribute to background, the use of anti-mouse CD32/CD
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