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- 详细信息
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- 技术资料
- 抗体名:
APC anti-human CD45
- 抗体英文名:
APC anti-human CD45
- 应用范围:
免疫荧光,流式
- 宿主:
小鼠
- 供应商:
上海善然生物
- 库存:
现货
- 抗原来源:
小鼠
- 保质期:
2-3年左右
- 适应物种:
人
- 标记物:
APC
- 克隆性:
单克隆
- 保存条件:
2-8度
- 形态:
液体
- 规格:
100 μg
APC anti-human CD45 Antibody
2D1
Catalog# / Size 368511 / 25 tests
368512 / 100 tests
Clone
Regulatory Status RUO
Other Names Leukocyte Common Antigen (LCA), T200
Isotype Mouse IgG1, κ
Description CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte
common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma
membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling
molecule that regulates a variety of cellular processes including cell growth, differentiation, cell
cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen
receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and
other Src family kinases. CD45 non-covalently associates with lymphocyte phosphataseassociated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind
galectin-1 and to be associated with several other cell surface antigens including CD1, CD2,
CD3, and CD4.
Product Details
Verified Reactivity Human
Antibody Type Monoclonal
Host Species Mouse
Immunogen Human PBMC
Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation The antibody was purified by affinity chromatography and conjugated with APC under optimal
conditions.
Concentration Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our
Certificate of Analysis online tool.)
Storage & Handling The antibody solution should be stored undiluted between 2°C and 8°C, and protected from
prolonged exposure to light. Do not freeze.
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