- ￥2960 - 10064
- 优爱
- 江苏南京
- UA010588
- 2025年12月22日
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100μg/500μg
| 规格： | 100μg | 产品价格： | ￥2960.0 |
|---|---|---|---|
| 规格： | 500μg | 产品价格： | ￥10064.0 |
The Bone Morphogenetic Protein (BMP) receptor activin receptor–like kinase 1 (Alk1), which is predominantly expressed in the vascular endothelium, has been shown to play a critical role in angiogenesis. Embryos lacking Alk1 die early during embryonic development due to impaired vascular remodeling and lack of perivascular cell coverage. In renal physiology, Alk1 has been suggested to play an important role in the regulation of extracellular matrix deposition, including collagen type I and fibronectin, and Alk1 heterozygosity has been associated with increased renal fibrosis in a mouse model of obstructive nephropathy, probably due to the decrease in the Alk1/Smad1 antifibrotic/protective signaling in renal fibroblasts.
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文献和实验cells. We present here (i) a detailed protocol for the production and purification of soluble recombinant NK cell receptors tagged with human IgG1-Fc (thus termed receptor-Fc chimera or receptor-Ig fusion protein) and (ii) a protocol for cell staining
【原创】Protein A Sepharose 之进化篇。。。
[img][/img]Protein A 柱之进化 Protein A是一种金黄色葡萄球菌细胞壁蛋白质，能特异性地与人和哺乳动物抗体（主要是IgG）的Fc区结合。因而，将Protein A 与琼脂糖凝胶以一定的方式结合，可制备用于抗体纯化的亲和填料。 早期的Protein A柱结合的都是天然Protein A。天然Protein A由5个IgG结合域和其它未知功能的非Fc结合域组成，分子量约42KD，结构如图1所示。这种柱子对IgG的亲和能力很强，可以吸附大量的lgG。但同时，天然
Transient Production of scFv-Fc Fusion Proteins in Mammalian Cells
Single chain Fv (scFv) antibody fragments fused to the human immunoglobulin G (IgG) Fc moiety obtain IgG-like properties, but nevertheless they are still encoded by a single gene. As transient production of scFv-Fc proteins in mammalians
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