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GAD65 Rabbit Polyclonal Antibo

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  • ¥400 - 900
  • 斯达特已认证
  • 浙江杭州
  • S0B1492
  • 2025年10月07日
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    2钻石会员
  • 企业认证

    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      <p>12 months from date of receipt / reconstitution, -20 °C as supplied</p>

    • 供应商

      斯达特

    • 规格

      25μl/100μl

    规格:25μl产品价格:¥400.0
    规格:100μl产品价格:¥900.0

    Glutamic acid decarboxylase 65 (GAD65) is an enzyme that synthesizes the inhibitory neurotransmitter γ-aminobutyric acid (GABA) from glutamate, playing a crucial role in the central nervous system. It is one of the two isoforms of glutamic acid decarboxylase, the other being GAD67. GAD65 is particularly notable for its dynamic structure and its role as a major autoantigen in type 1 diabetes (T1D), with autoantibodies against it often present before the clinical onset of the disease. Structurally, GAD65 forms obligate functional dimers and consists of three domains: the N-terminal domain (NTD), the pyridoxal-5'-phosphate (PLP)-binding domain, and the C-terminal domain (CTD). Its catalytic loop (CL) is dynamic, which contrasts with the stable conformation of GAD67's CL.

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    图标文献和实验
    相关实验
    • Polyclonal Antibody Production

      Zealand White Rabbits and have them delivered to the ARC. Don’t put all your eggs in one basket only using one rabbit. Let them get accustomed to there home there for two weeks before the first pre-bleed. Pre-bleed        

    • Polyclonal Antibody Production

        Polyclonal Antibody Production Very useful for rapid and simple generation of antibodies for western blots, ELISA assays, and immunoprecipitation.     Rabbit Immunization Initial Preparation Your antigen

    • Generation and Selection of Rabbit Antibody Libraries by Phage Display

      The rabbit antibody repertoire is an exceptional source for both polyclonal antibodies (pAbs) and monoclonal antibodies (mAbs) that combine high specificity with high avidity and affinity, respectively. In contrast to rabbit pAbs

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