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Bim Recombinant Rabbit mAb (S-

994-29)
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  • ¥600 - 2100
  • 斯达特已认证
  • 浙江杭州
  • S0B0826
  • 2025年07月16日
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    2钻石会员
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      <p>12 months from date of receipt / reconstitution, -20 °C as supplied</p>

    • 供应商

      斯达特

    • 规格

      25μl/100μl

    规格:25μl产品价格:¥600.0
    规格:100μl产品价格:¥2100.0

    BIM belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BIM contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. Bim expression and activity are regulated at the transcriptional, translational and post-translational levels; coordinated expression and activity of Bim shape immune responses, and ensure tissue integrity. Cancer cells develop mechanisms that suppress Bim expression, which allows for tumor progression and metastasis.

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