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- 亚科因(Abbkine)
- PRP1174
- 湖北武汉
- 2025年11月24日
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- 库存：
999
- 供应商：
亚科因(Abbkine)
- 英文名：
Mouse TNF beta Protein, His tag (Animal-Free)
- 规格：
5 µg/20 µg/100 µg/1 mg
| 规格： | 5 µg | 产品价格： | ￥588.0 |
|---|---|---|---|
| 规格： | 20 µg | 产品价格： | ￥1498.0 |
| 规格： | 100 µg | 产品价格： | ￥3389.0 |
| 规格： | 1 mg | 产品价格： | 询价 |
重组小鼠肿瘤坏死因子-β，His-标签（无动物源）
PRP1174 | Mouse TNF beta Protein, His tag (Animal-Free)
产品描述
本产品为大肠杆菌表达的重组小鼠肿瘤坏死因子-β（TNF-β），含His标签并通过无动物源工艺生产。氨基酸序列覆盖Leu 34-Leu 202区域，分子量范围为11-17 kDa。
关键特性
- 高生物活性：ED50 ≤0.3 ng/mL（PBMC增殖诱导实验）
- 超低内毒素：＜0.1 EU/µg（LAL法检测）
- 严格质控：SDS-PAGE纯度＞98%
- 无动物源保障：全程无动物源性成分
产品规格
| 表达系统 | 大肠杆菌 |
| 蛋白形态 | 冻干粉（PBS pH8.0缓冲体系） |
| 复溶浓度 | ≥100 µg/mL（推荐配套复溶缓冲液） |
| 检测指标 | TNFSF1B, LT-α等淋巴毒素相关标志物 |
保存与运输
- 冻干状态：-20°C保存1年
- 复溶后：4°C保存≤7天，-20°C/-80°C分装保存3-6个月
- 运输保障：蓝冰冷链运输
订购信息
| 规格 | 价格 | 货期 |
|---|---|---|
| 5 µg | ¥588 | 次日发货 |
| 20 µg | ¥1,498 | 次日发货 |
| 100 µg | ¥3,389 | 咨询确认 |
| 1 mg | 定制生产 | 咨询确认 |
重要提示
※ 使用前需离心处理，避免反复冻融
※ 仅限研究用途，不可用于临床诊断
※ 具体应用需遵守当地法规和知识产权要求
生物学背景
TNF-β（淋巴毒素α）是TNF超家族成员，具有介导炎症反应、免疫调节和抗病毒功能。该19kDa蛋白通过结合TNF受体参与次级淋巴器官发育，并在肿瘤细胞杀伤中发挥重要作用（UniProt ID：P09225）。
注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。
Recombinant Mouse Tumor Necrosis Factor-beta, His-Tag (Animal-Free)
PRP1174 | Mouse TNF beta Protein, His tag (Animal-Free)
Product Description
This product is a recombinant mouse Tumor Necrosis Factor-beta (TNF-β) expressed in E. coli, containing a His-tag and produced through an animal-free process. The amino acid sequence covers the region Leu 34-Leu 202, with a molecular weight range of 11-17 kDa.
Key Features
- High Bioactivity: ED50 ≤0.3 ng/mL (PBMC proliferation induction assay)
- Ultra-Low Endotoxin: ＜0.1 EU/µg (LAL assay)
- Rigorous Quality Control: SDS-PAGE purity >98%
- Animal-Free Assurance: Entirely free of animal-derived components
Product Specifications
| Expression System | E. coli |
| Protein Form | Lyophilized powder (PBS pH8.0 buffer system) |
| Reconstitution Concentration | ≥100 µg/mL (recommended reconstitution buffer included) |
| Detection Indicators | TNFSF1B, LT-α, and other lymphotoxin-related markers |
Storage and Shipping
- Lyophilized State: Store at -20°C for 1 year
- After Reconstitution: Store at 4°C for ≤7 days, or aliquot and store at -20°C/-80°C for 3-6 months
- Shipping Assurance: Shipped with blue ice cold chain
Ordering Information
| Specification | Price | Lead Time |
|---|---|---|
| 5 µg | ¥588 | Next day delivery |
| 20 µg | ¥1,498 | Next day delivery |
| 100 µg | ¥3,389 | Consult for confirmation |
| 1 mg | Custom production | Consult for confirmation |
Important Notes
※ Centrifuge before use, avoid repeated freeze-thaw cycles
※ For research use only, not for clinical diagnosis
※ Specific applications must comply with local regulations and intellectual property requirements
Biological Background
TNF-β (Lymphotoxin-alpha) is a member of the TNF superfamily, involved in mediating inflammatory responses, immune regulation, and antiviral functions. This 19kDa protein participates in the development of secondary lymphoid organs by binding to TNF receptors and plays a significant role in tumor cell killing (UniProt ID: P09225).
Note: The above information may change due to product optimization and upgrades. For specific details, please consult Abbkine.
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