重组人骨形态发生蛋白8a，His-标签（无动物源）（BMP-

重组人骨形态发生蛋白8a（BMP-8a）His标签（无动物源）

英文名称：Human BMP-8a Protein, His tag (Animal-Free) | 货号：PRP1197

产品概述

本产品为核心级细胞培养用重组蛋白，隶属于细胞因子及蛋白类别，通过大肠杆菌表达系统生产，严格符合无动物源（Animal-Free）要求。适用于细胞分化、信号通路研究等细胞类实验。

关键参数

• 来源种属：人源（氨基酸序列：Ala264-His402，UniProt ID：Q7Z5Y6）
• 活性验证：ED₅₀=10-19.4 ng/mL（ATDC5细胞碱性磷酸酶诱导实验）
• 纯度检测：＞98%（SDS-PAGE）
• 内毒素：＜0.1 EU/μg（LAL法测定）
• 产品形式：冻干粉（含20mM sodium citrate，0.2 M NaCl，pH3.5缓冲液）

质量控制

• 分子量：16.61 kDa（139个氨基酸）
• 标签系统：C端His标签
• 宿主残留：大肠杆菌表达系统

使用指南

• 复溶建议：使用配套缓冲液复溶至≥100 µg/mL
• 保存条件： - 冻干粉：-20°C保存（有效期12个月） - 复溶后：2-8°C保存≤7天；含稳定剂稀释液可-20°C/-80°C保存3-15个月
• 运输方式：蓝冰冰链运输

规格与交付

• 5 μg ￥588 | 次日发货
• 20 μg ￥1498 | 次日发货
• 100 μg ￥5998 | 咨询货期
• 1 mg | 定制生产

重要声明

⚠️ 本产品仅限研究用途，不适用于人类或临床诊断。使用前请充分阅读产品说明书并遵守相关实验规范。

技术背景

BMP-8a属TGF-β超家族成员，通过结合TGF-β受体激活SMAD信号通路，参与骨形态发生、软骨发育及胰岛素分泌调控（Gene ID：353500）。

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注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Recombinant Human Bone Morphogenetic Protein 8a (BMP-8a) His Tag (Animal-Free)

Product Name: Human BMP-8a Protein, His tag (Animal-Free) | Catalog Number: PRP1197

Product Overview

This product is a core-grade recombinant protein for cell culture, classified under the cytokines & proteins category. It is produced using an E. coli expression system and strictly complies with Animal-Free requirements. Suitable for cell-based assays such as cell differentiation and signaling pathway research.

Key Specifications

• Species: Human (Amino Acid Sequence: Ala264-His402, UniProt ID: Q7Z5Y6)
• Activity: ED<sub>50</sub>=10-19.4 ng/mL (ATDC5 cell alkaline phosphatase induction assay)
• Purity: >98% (SDS-PAGE)
• Endotoxin: <0.1 EU/μg (LAL assay)
• Formulation: Lyophilized powder (in 20mM sodium citrate, 0.2 M NaCl, pH3.5 buffer)

Quality Control

• Molecular Weight: 16.61 kDa (139 amino acids)
• Tag System: C-terminal His tag
• Host Residue: E. coli expression system

Usage Guidelines

• Reconstitution: Reconstitute with provided buffer to ≥100 µg/mL
• Storage: - Lyophilized: -20°C (12 months shelf life) - Reconstituted: 2-8°C for ≤7 days; with stabilizer-containing diluent: -20°C/-80°C for 3-15 months
• Shipping: Blue ice transportation

Specifications & Delivery

• 5 μg ¥588 | Next-day delivery
• 20 μg ¥1498 | Next-day delivery
• 100 μg ¥5998 | Lead time inquiry required
• 1 mg | Custom production

Important Notice

⚠️ For research use only. Not intended for human or diagnostic use. Please read the product manual thoroughly and follow relevant experimental protocols.

Technical Background

BMP-8a belongs to the TGF-β superfamily, activating SMAD signaling pathways through TGF-β receptor binding, and participates in bone morphogenesis, cartilage development, and insulin secretion regulation (Gene ID: 353500).

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Note: The above information may be subject to changes due to product optimization. Please contact AcroBiosystems for updated details.