重组人可溶性RANK配体（sRANKL）

重组人可溶性RANK配体（sRANKL）

PRP1033 | Human sRANKL protein

▍核心参数

• 产品类型：无标签人源细胞因子（大肠杆菌表达）
• 活性验证：功能性ELISA检测显示OPG结合EC₅₀=188ng/mL
• 纯度标准：≥98%（SDS-PAGE检测）
• 内毒素：<0.1 EU/μg（LAL法检测）

▍关键特性

• 175个氨基酸构成（Glu143-Asp317），分子量19kDa
• 冻干制剂含150mM NaCl + 20mM Tris (pH8.0)
• 推荐复溶浓度≥100μg/mL，稀释后4℃稳定2-7天
• 长期保存需-20℃干燥环境，建议添加0.1% HSA/BSA

▍功能应用

• 调控破骨细胞分化的关键配体（RANKL/OPG通路）
• 参与T细胞-树突状细胞相互作用调控
• 适用于骨代谢、免疫调控相关机制研究

▍规格与交付

规格	价格（CNY）	货期
2 μg	588	现货（次日发货）
20 μg	1,498
200 μg	7,296
1 mg	请咨询

▍注意事项

• 使用前需离心处理冻干粉
• 禁止用于人体或临床诊断
• 运输全程保持2-8℃（蓝冰运输）

* 本产品受专利保护，应用前请确认相关知识产权状态。完整序列信息参见UniProt：O14788 ```

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

Recombinant Human Soluble RANK Ligand (sRANKL)

PRP1033 | Human sRANKL protein

▍Key Parameters

• Product Type: Tag-free human cytokine (E. coli expression)
• Activity Validation: Functional ELISA demonstrated OPG binding EC₅₀=188ng/mL
• Purity Standard: ≥98% (SDS-PAGE analysis)
• Endotoxin: <0.1 EU/μg (LAL assay)

▍Key Features

• 175 amino acids (Glu143-Asp317), molecular weight 19kDa
• Lyophilized formulation contains 150mM NaCl + 20mM Tris (pH8.0)
• Recommended reconstitution concentration ≥100μg/mL, stable for 2-7 days at 4°C after dilution
• For long-term storage: -20°C in dry environment, recommended to add 0.1% HSA/BSA

▍Functional Applications

• Key ligand regulating osteoclast differentiation (RANKL/OPG pathway)
• Involved in T cell-dendritic cell interaction regulation
• Suitable for bone metabolism and immune regulation mechanism studies

▍Specifications & Delivery

Specification	Price (CNY)	Lead Time
2 μg	588	In stock (shipped next day)
20 μg	1,498
200 μg	7,296
1 mg	Please inquire

▍Precautions

• Centrifuge lyophilized powder before use
• Not for human use or clinical diagnosis
• Maintain 2-8°C during transportation (blue ice shipping)

* This product is patent protected. Please verify intellectual property status before application. Complete sequence information available at UniProt: O14788

Note: The above information may change due to product optimization and upgrades. Please contact Acro Biosystems for specific details.