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huayun / β-NGF/ NGF/ NGFB (Ser

122-Gly241), Mouse, Recombinant (暂不出售),HYPC5089
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  • ¥2640
  • 华韵生物(Huayunbio)
  • HYPC5089
  • 2025年07月14日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 供应商

      广州华韵生物科技有限公司

    • 规格

      10µg

    产品信息

    别名Beta-Nerve Growth Factor; Beta-NGF; NGF
    物种Mouse
    表达宿主E.coli
    序列信息asd
    检索号P01139
    分子量13.5 kDa
    表观分子量14 kDa
    生物活性 Testing in progress

    产品特性

    纯度 >95% as determined by reducing SDS-PAGE.
    内毒素< 1.0 EU per µg as determined by LAL test.
    保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2~8℃ for 2~7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
    运输 Ambient temperature or ice pack.
    制剂Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0
    复融Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    背景介绍

    NGF is the first member discovered in the Neurotrophin family, which includes brain-Derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These Proteins belong to the cysteine-knot family of Growth Factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. β-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its Receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.

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